Hubei Yuancheng Saichuang Technology Co.,Ltd

Product Name Exenatide Acetate (Exendin-4) Sequence H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu- Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu- Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser- Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2 Cas No. 141758-74-9 Molecular Formula C184H282N50O60 S Molecular Weight 4186.66 Purity (HPLC) 98.0%min. Appearance? White powder Single Impurity(HPLC)? 1.0%max Amino Acid Composition? ±10% of theoretical Peptide Content(N%) ?≥80.0% Water Content(Karl Fischer)? ≤10.0% Acetate Content(HPIC) ≤12.0% MS(ESI) ?Consistent Mass Balance? 95.0~105.0% Application: Exenatide is believed to facilitate glucose control in at least five ways: 1. Exenatide augments pancreas response and more appropriate amount of insulin that helps lower the rise in blood sugar from eating. 2. Exenatide also suppresses pancreatic release of glucagon, which prevents hyperglycemia (high blood sugar levels). 3. Exenatide helps slow down gastric emptying and thus decreases the rate at which meal-derived glucose appears in the bloodstream. 4. Exenatide has a subtle yet prolonged effect to reduce appetite, promote satiety via hypothalamic receptors. 5. Exenatide reduces liver fat content. Fat accumulation in the liver or nonalcoholic fatty liver disease (NAFLD) is strongly related with several metabolic disorders.